Dr Sarandeep Singh Puri
Associate Professor, Pathology, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India.
Title: To study the association of benign breast lesions with malignant lesions of breast in histopathology.
Biography
Biography: Dr Sarandeep Singh Puri
Abstract
Background- Breast cancer is the most common cancer in women It is the leading cause of death from cancer for women in age group 40-44 years. Benign diseases are important risk factors for later development of breast cancer. Aims and Objectives-To study the incidence of association of benign breast disease in breast malignancy. To study the epidemiology of benign breast disease associated with malignancy. To study the pattern of benign breast diseases associated with carcinoma breast. To establish the relative significance of development of carcinoma with preexisting benign breast diseases. Material and Methods- All patients who underwent mastectomy for carcinoma breast were recorded. No of patients -50 . Study Period- Sep 22’ to Feb 2023. Sections were taken from tumor mass and surrounding normal tissue 2cm away from tumor mass. All sections were processed and stained with H and E stain. Results- Among the cases studied most of the patients observed were of age group 40-50 years . 56 percent patients strong family history. Most of women were of perimenopausal group. Out of 50 cases Non proliferative lesions 44%,Ductal carcinoma in situ 16%,Calcification 12%,Ductal hyperplasia without atypia 8%,Apocrine metaplasia 8%,Adenosis 8%,Fibrocystic disease 4%. Among the cases studied most common premalignant condition observed was ductal carcinoma in situ followed by ductal hyperplasia without atypia,adenosis and apocrine metaplasia. Conclusion- Benign changes observed in surrounding normal tissue of mastectomy specimen support the finding that these conditions are associated with the breast cancer risk.