Breast Cancer and Genetics
The two most common genetic risk factors for breast cancer are the BRCA1 & BRCA2 genes. Approximately 5% of all breast cancers are caused by a recognised specific genetic predisposition due to germ line mutations of one of two different genes: BRCA1 located on Chromosome 17q, BRCA2 located on Chromosome 13q. BRCA1 mutations also predispose to carcinoma of the ovary and possibly carcinoma of the Fallopian tube. The risk of developing breast cancer among carriers is around 55% by age 70. BRCA2: The product of BRCA2 is involved in controlling gene function and DNA repair. Gene function involves in transcriptional activation and completion of cell division by cytokinesis. Majority of BRCA2-associated tumours are invasive ductal, no special-type tumours.
Related Conference of Breast Cancer and Genetics
2 nd International Conference on Pathology and Pathological Disorders
17th Global Experts Meeting on Pathology and Laboratory Medicine
13th International Summit on Gynaecology, Obstetrics and Women’s Health
Breast Cancer and Genetics Conference Speakers
Recommended Sessions
- Breast Cancer and Genetics
- Breast Cancer Grading and Staging
- Breast Cancer pathology
- Breast Cancer Pathology in Pregnancy
- Breast Cancer Prevention
- Breast Cancer Surgery
- Breast Cancer: Challenges, Breakthroughs
- Breast Diseases
- Breast Implants
- Breast Pathology and Immunohistochemistry
- Breast Pathology Treatment and Drugs
- Case study and Case Reports
- Latest Advances and Innovative Therapeutic Approaches
- Male Breast cancer
- Nursing and Palliative care rehabilitation
- Screening, Monitoring and Diagnosis
- Special Types of Breast Cancer
- Women’s Health and Fitness
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