Breast Cancer and Genetics

The two most common genetic risk factors for breast cancer are the BRCA1 & BRCA2 genes. Approximately 5% of all breast cancers are caused by a recognised specific genetic predisposition due to germ line mutations of one of two different genes: BRCA1 located on Chromosome 17q, BRCA2 located on Chromosome 13q. BRCA1 mutations also predispose to carcinoma of the ovary and possibly carcinoma of the Fallopian tube. The risk of developing breast cancer among carriers is around 55% by age 70. BRCA2: The product of BRCA2 is involved in controlling gene function and DNA repair. Gene function involves in transcriptional activation and completion of cell division by cytokinesis.  Majority of BRCA2-associated tumours are invasive ductal, no special-type tumours

  • Testing for BRCA1 & 2
  • Ataxia telangiectasia mutation (ATM)
  • Hereditary breast cancers genes
  • Prognosis

Related Conference of Breast Cancer and Genetics

March 20-21, 2019

International Conference on Molecular Pathology

Paris | France
April 22-23, 2019

16th Annual Conference on Laboratory Medicine & Pathology

Kuala Lumpur, Malaysia
May 9-10, 2019

17th European Pathology Congress

| Amsterdam, Netherlands
June 28-29, 2019

Breast Pathology 2019

Oslo, Norway
July 29-30, 2019

17th Asia Pacific Pathology Congress

Mercure Albert Park, Melbourne, Australia
November 08 09, 2019

18th Global Congress on Pathology

San Francisco | California | United States
November 19-20, 2019

2nd European Pathology and Infectious Disease Conference

Helsinki, Finland

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